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KMID : 0614620070500030145
Korean Journal of Gastroenterology
2007 Volume.50 No. 3 p.145 ~ p.156
Review : Intestinal Neuronal Dysplasia
Seo Jeong-Kee

Abstract
Intestinal neuronal dysplasia (IND) type B is a disease of the submucosal plexus of intestine manifesting chronic
intestinal obstruction or severe chronic constipation. IND is one of intestinal dysganglionoses and clinically closely
associated with Hirschsprung¡¯s disease. Until recently, it is not fully clear whether IND is a congenital malformation or an acquired secondary condition related to some gastrointestinal problems. However, recently published data and consensus reports have enhanced our understanding of the pathogenesis and management of IND. The aim of this paper was to review the current state of knowledge regarding the controversial issues of IND including the etiology, classification, diagnostic criteria, and available therapeutic intervention. (Korean J Gastroenterol 2007;50:145-156)
KEYWORD
Intestinal neuronal dysplasia, Chronic intestinal pseudo-obstruction, Hirschsprung`s disease
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